10 Winning Picks for Your March Madness Bracket

Published On Thu Mar 20 2025
10 Winning Picks for Your March Madness Bracket

ChatGPT's March Madness AI Predictions & NCAA Tournament Best Bets

We've already turned to ChatGPT for its March Madness AI bracket predictions, but we're gathering all of its best bets and picks ahead of the NCAA Tournament first round. From its March Madness championship prediction to its best first-round upsets, we're taking a look at the best value bets for the NCAA Tournament according to ChatGPT.

👉 Looking for the perfect March Madness bracket? We simulated every NCAA Tournament game 1,000 times to help with your bracket predictions.

Duke Predicted to Win NCAA Tournament

There must be a little bit of human hiding inside that robot's mind because it has the same March Madness prediction as everyone else: ChatGPT predicts Duke will win the NCAA Tournament.

📊 Duke's best odds to win NCAA Tournament: +320 via DraftKings Terms and conditions apply.

It shouldn't surprise anyone to see ChatGPT pick the Blue Devils, who are the most popular choice among March Madness media expert bracket picks and our very own college basketball experts at Sportsbook Review, too.

It's easy to see why - Duke boasts three of the best players in March Madness in Cooper Flagg, Kon Knueppel, and Khaman Maluach, while veteran leader Tyrese Proctor is perhaps the most overqualified "role player" in the country. That's why the Blue Devils are dealing among the favorites by the March Madness odds entering the first round.

👉 More March Madness predictions: One of these 8 teams will win the NCAA Tournament

UC San Diego's Surprise Run

Our ChatGPT bracket predictions didn't offer many candidates with most potential Cinderella teams losing in the first or second round. That said, it did pick one double-digit seed to advance all the way to the Sweet 16.

📊 UC San Diego's best odds to reach Sweet 16: +390 via DraftKings

UC San Diego

UC San Diego is one of the trendiest picks in the March Madness bracket this year after posting a 30-4 record behind star transfer Aniwaniwa Tait-Jones, who is averaging 19.5 points on 57.6% shooting - both of which rank in the top 30 nationally.

Our college basketball expert Rob Paul also has the Tritons advancing to the Sweet 16 in his March Madness expert bracket, and you can still get juicy odds on the Big West champions to reach the Sweet 16 via DraftKings.

👉 Looking for the next Cinderella? We broke down our March Madness bracket sleepers including our best upset picks and Cinderellas in every region.

Drake's Upset Potential

Nothing beats nailing one of your March Madness upset predictions, especially when it involves a double-digit seed from a conference nobody has heard of.

📊 Drake's best odds to beat Missouri: +220 via bet365 *Deposit required. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply.

While ChatGPT picked seven double-digit seeds to advance in the first round - including two No. 12 seeds - none have longer odds across our best sportsbooks than Drake to advance to the second round of the NCAA Tournament.

Drake

That feels like an oversight by bet365 and others, as the Bulldogs have a veteran lineup led by a slew of former D-II transfers and force turnovers at the highest rate in the country (14.6%). That sounds like the perfect upset recipe for one of this year's best March Madness Giant Killers.

Texas Tech's Dark Horse Run

For all of the upsets that have come to define the NCAA Tournament, the final four teams in the 68-team field tend to be mostly the March Madness top seeds.

📊 Texas Tech's best odds to reach Final Four: +560 via Caesars New users only. Must use promo code. Min. $10 deposit. Max. bonus is ten 100% Profit Boost tokens. Profit Boost tokens expire in 14 days. Void where prohibited. Full terms.

Even though Texas ranks seventh in KenPom with the sixth-best offensive efficiency in the country, the Red Raiders were denied a top-two seed and landed in arguably the toughest region in the NCAA Tournament.

None of that is deterring ChatGPT, which picked Grant McCasland's group to win the West Region and reach the Final Four for the first time since a trip to the title game in 2019. And a bet on that happening would turn a $10 wager into a $56 profit at Caesars.

👉 Too much chalk in your bracket? Check out our March Madness Final Four expert picks with our best sleepers and long shots to reach the Final Four.

Ready to place your March Madness bets? Check out the best March Madness betting promos from the best March Madness betting sites as determined by our expert team at Sportsbook Review.

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